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KMID : 0357319920270030283
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Journal of the Korean Society for Microbiology
1992 Volume.27 No. 3 p.283 ~ p.288
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Prevalence of Antibodies to the Phase I Antigen of Cosiella burnetii, the Q Fever Agent among Residents in Korea
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조상래
이미경/이재면/김주덕/이원영
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Abstract
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Recent case reports of Q fever in Korea brought an interest in determining the estent of Coxiella burnetii infection among resious geographical areas. In thes study, therefore, a total of 746 serum samples were obtained from 176 patients with
fever
of
unknown origin, 132 patients suspected having tuberculosis, 10 patients infected with rickettsia tsutsugamushi, and 428 residens from Kanghwa-kun of kyeonggi-do, Seoul city, the eastern part of Kangweon-do, the Kyeongsangbuk-do area and Keoje-kun
of
Kyeongsangnam-do and were examined for the presence of antibodies to C. burnetii phase I antigen by indirect fluorescent antibody (IFA) test. There were two serum samples reacting with the phse I antigen at 1 : 160 and 1 : 640 dilutions,
respectively,
which were obtained from patients hospitalized in 1987 due to fever of unknown origin and rash. In addition, one patient visited to the chest clinic had an IFA titer of 1:20, which was considered seropositive. However, the rest of the serum
samples
were
not reactie with C. burnetii phase I antigen at 1:20 dilutin. Thus, this study indicated clearly that C. burnetii infections occurred back in 1987 in Korea, but the exposure of general populations in Korea to the organisms seemed not extensive.
Further
seroepidemiological studies using phase Ⅱ antigen aer desirable to assess accurately the extent of C. burnetii transmission among risk groups such as farmers, slaughter house workers, veterinarians, ete., who may contact with the animals
infected
with
the organisms.
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KEYWORD
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